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Uptake and transfection with polymeric nanoparticles are dependent on polymer end-group structure, but largely independent of nanoparticle physical and chemical properties

Development of non-viral particles for gene delivery requires a greater understanding of the properties that enable gene delivery particles to overcome the numerous barriers to intracellular DNA delivery. Linear poly(beta-amino) esters (PBAE) have shown substantial promise for gene delivery, but the...

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Main Authors: Sunshine, Joel C., Peng, Daniel Y., Green, Jordan J.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779641/
https://ncbi.nlm.nih.gov/pubmed/22970908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp3004176
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