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Effects of Base Polymer Hydrophobicity and End Group Modification on Polymeric Gene Delivery

A new 320 member polymer library of end-modified poly(beta amino) esters was synthesized. This library was chosen such that small differences to the structures of component backbone, side-chain, and end-group monomers could be systematically and simultaneously evaluated. The in vitro transfection ef...

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Detalhes bibliográficos
Main Authors: Sunshine, Joel C., Akanda, Marib I., Li, David, Kozielski, Kristen L., Green, Jordan J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959121/
https://ncbi.nlm.nih.gov/pubmed/21888340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm200807s
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