Indoleamine 2,3-dioxygenase Activity Contributes to Local Immune Suppression in the Skin Expressing Human Papillomavirus Oncoprotein E7

Chronic infection of anogenital epithelium with human papillomavirus (HPV) promotes development of cancer. Many pathogens evoke immunosuppressive mechanisms to enable persistent infection. We have previously shown that grafted skin expressing HPV16 E7 oncoprotein from a keratin-14 promoter (K14E7) i...

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Hlavní autoři: Mittal, D, Kassianos, AJ, Tran, LS, Bergot, AS, Gosmann, C, Hofmann, J, Blumenthal, A, Leggatt, GR, Frazer, IH
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779505/
https://ncbi.nlm.nih.gov/pubmed/23652797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2013.222
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