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Overcoming Synthetic Challenges of Oridonin A-Ring Structural Diversification: Regio- and Stereoselective Installation of Azides and 1,2,3-Triazoles at the C-1, C-2, or C-3 Position

[Image: see text] Efficient and concise synthetic approaches have been developed for the rapid and diverse installation of azide functionalities at the C-1, C-2 or C-3 of oridonin (1) with highly controlled regio- and stereoselectivity, while keeping key reactive pharmacophores intact by utilizing u...

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Hlavní autoři: Ding, Chunyong, Zhang, Yusong, Chen, Haijun, Wild, Christopher, Wang, Tianzhi, White, Mark A., Shen, Qiang, Zhou, Jia
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779473/
https://ncbi.nlm.nih.gov/pubmed/23834026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol4015865
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