Enveloped Viruses Disable Innate Immune Responses in Dendritic Cells by Direct Activation of TAM Receptors

Upon activation by the ligands Gas6 and Protein S, TAM receptor tyrosine kinases promote phagocytic clearance of apoptotic cells and downregulate immune responses initiated by Toll-like receptors and type I interferons (IFNs). Many enveloped viruses display the phospholipid phosphatidylserine on the...

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Autors principals: Bhattacharyya, Suchita, Zagórska, Anna, Lew, Erin D., Shrestha, Bimmi, Rothlin, Carla V., Naughton, John, Diamond, Michael S., Lemke, Greg, Young, John A.T.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779433/
https://ncbi.nlm.nih.gov/pubmed/23954153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2013.07.005
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