The Proline-Rich Motif of the proDer p 3 Allergen Propeptide Is Crucial for Protease-Protease Interaction

The majority of proteases are synthesized in an inactive form, termed zymogen, which consists of a propeptide and a protease domain. The propeptide is commonly involved in the correct folding and specific inhibition of the enzyme. The propeptide of the house dust mite allergen Der p 3, NPILPASPNAT,...

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Detalhes bibliográficos
Main Authors: Dumez, Marie-Eve, Herman, Julie, Campisi, Vincenzo, Bouaziz, Ahlem, Rosu, Frédéric, Luxen, André, Vandenberghe, Isabel, de Pauw, Edwin, Frère, Jean-Marie, Matagne, André, Chevigné, Andy, Galleni, Moreno
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779199/
https://ncbi.nlm.nih.gov/pubmed/24073192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068014
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