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Profiling the Extended Cleavage Specificity of the House Dust Mite Protease Allergens Der p 1, Der p 3 and Der p 6 for the Prediction of New Cell Surface Protein Substrates

House dust mite (HDM) protease allergens, through cleavages of critical surface proteins, drastically influence the initiation of the Th2 type immune responses. However, few human protein substrates for HDM proteases have been identified so far, mainly by applying time-consuming target-specific indi...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Jacquet, Alain, Campisi, Vincenzo, Szpakowska, Martyna, Dumez, Marie-Eve, Galleni, Moreno, Chevigné, Andy
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535866/
https://ncbi.nlm.nih.gov/pubmed/28654001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071373
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