4-Ethylphenyl-Cobalamin Impairs Tissue Uptake of Vitamin B(12) and Causes Vitamin B(12) Deficiency in Mice

Co(β)-4-ethylphenyl-cob(III) alamin (EtPhCbl) is an organometallic analogue of vitamin B(12) (CNCbl) which binds to transcobalamin (TC), a plasma protein that facilitates the cellular uptake of cobalamin (Cbl). In vitro assays with key enzymes do not convert EtPhCbl to the active coenzyme forms of C...

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Detaylı Bibliyografya
Asıl Yazarlar: Mutti, Elena, Ruetz, Markus, Birn, Henrik, Kräutler, Bernhard, Nexo, Ebba
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779197/
https://ncbi.nlm.nih.gov/pubmed/24073261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075312
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