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The EBAX-type Cullin-RING E3 Ligase and Hsp90 Guard the Protein Quality of the SAX-3/Robo Receptor in Developing Neurons
Although protein quality control (PQC) is generally perceived as important for the development of the nervous system, the specific mechanisms of neuronal PQC have remained poorly understood. Here, we report that C. elegans EBAX-1 (Elongin BC-Binding AXon regulator), a conserved BC-box protein, regul...
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Huvudupphovsmän: | , , , , , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
2013
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3779136/ https://ncbi.nlm.nih.gov/pubmed/24012004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.06.035 |
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