Voltage sensitivity of M(2) muscarinic receptors underlies the delayed rectifier-like activation of ACh-gated K(+) current by choline in feline atrial myocytes

Choline (Ch) is a precursor and metabolite of the neurotransmitter acetylcholine (ACh). In canine and guinea pig atrial myocytes, Ch was shown to activate an outward K(+) current in a delayed rectifier fashion. This current has been suggested to modulate cardiac electrical activity and to play a rol...

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Bibliographic Details
Main Authors: Navarro-Polanco, Ricardo A, Aréchiga-Figueroa, Iván A, Salazar-Fajardo, Pedro D, Benavides-Haro, Dora E, Rodríguez-Elías, Julio C, Sachse, Frank B, Tristani-Firouzi, Martin, Sánchez-Chapula, José A, Moreno-Galindo, Eloy G
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2013
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779116/
https://ncbi.nlm.nih.gov/pubmed/23652593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.255166
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