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Quantifying the origins of population variability in cardiac electrical activity through sensitivity analysis of the electrocardiogram
Altered function of ion channels in the heart can increase the risk of sudden arrhythmic death. Hundreds of genetic variants exist in these cardiac ion channel genes. The challenge is how to interpret the effects of multiple conductance perturbations on the complex multi-variable cardiac electrical...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3779112/ https://ncbi.nlm.nih.gov/pubmed/23551947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.251710 |
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