Development of a simple, rapid, sensitive, high-throughput luciferase reporter based microneutralization test for measurement of virus neutralizing antibodies following Respiratory Syncytial Virus vaccination and infection

We have established a new reporter gene-based RSV neutralization test using Renilla luciferase. The RSV-Luciferase Neutralization Test (RSV-Luc-NeuT) is a simple, rapid, high throughput, and less labor intensive functional serological assay than the traditional RSV-PRNT, capable of measuring a broad...

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Autores principales: Fuentes, Sandra, Crim, Roberta L., Beeler, Judy, Teng, Michael N., Golding, Hana, Khurana, Surender
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779065/
https://ncbi.nlm.nih.gov/pubmed/23742994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.05.088
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