Depletion of Bone Marrow-derived Macrophages Perturbs the Innate Immune Response to Surgery and Reduces Postoperative Memory Dysfunction

BACKGROUND: According to rodent models of postoperative cognitive decline, activation of the innate immune response following aseptic surgical trauma results in the elaboration of hippocampal proinflammatory cytokines, which are capable of disrupting long-term potentiation, the neurobiologic correla...

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Bibliografiske detaljer
Main Authors: Degos, Vincent, Vacas, Susana, Han, Zhenying, van Rooijen, Nico, Gressens, Pierre, Su, Hua, Young, William L., Maze, Mervyn
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779063/
https://ncbi.nlm.nih.gov/pubmed/23426204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e3182834d94
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