Nodal regulates energy metabolism in glioma cells by inducing expression of hypoxia-inducible factor 1α

BACKGROUND: A shift in glucose metabolism from oxidative phosphorylation to anaerobic glycolysis is the biochemical hallmark of malignant cancer cells. METHODS: In the present study, we demonstrated that Nodal stimulated the expression of glycolytic enzymes and decreased reliance on mitochondrial ox...

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Bibliographische Detailangaben
Hauptverfasser: Lai, Jing-Huei, Jan, Hsun-Jin, Liu, Li-Wen, Lee, Chin-Cheng, Wang, Shyang-Guang, Hueng, Dueng-Yuan, Cheng, Yung-Yen, Lee, Horng-Mo, Ma, Hsin-I
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
Basic and Translational Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779039/
https://ncbi.nlm.nih.gov/pubmed/23911596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not086
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