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Accelerated direct reprogramming of fibroblasts into cardiomyocyte-like cells with the MyoD transactivation domain

AIMS: Fibroblasts can be directly reprogrammed to cardiomyocyte-like cells by introducing defined genes. However, the reprogramming efficiency remains low, delaying the clinical application of this strategy to regenerative cardiology. We previously showed that fusion of the MyoD transactivation doma...

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Detalhes bibliográficos
Main Authors: Hirai, Hiroyuki, Katoku-Kikyo, Nobuko, Keirstead, Susan A., Kikyo, Nobuaki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778960/
https://ncbi.nlm.nih.gov/pubmed/23794713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvt167
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