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Accelerated direct reprogramming of fibroblasts into cardiomyocyte-like cells with the MyoD transactivation domain

AIMS: Fibroblasts can be directly reprogrammed to cardiomyocyte-like cells by introducing defined genes. However, the reprogramming efficiency remains low, delaying the clinical application of this strategy to regenerative cardiology. We previously showed that fusion of the MyoD transactivation doma...

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Bibliographic Details
Main Authors: Hirai, Hiroyuki, Katoku-Kikyo, Nobuko, Keirstead, Susan A., Kikyo, Nobuaki
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778960/
https://ncbi.nlm.nih.gov/pubmed/23794713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvt167
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