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c-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis

Although the sebaceous gland (SG) plays an important role in skin function, the mechanisms regulating SG differentiation and carcinoma formation are poorly understood. We previously reported that c-MYC overexpression stimulates SG differentiation. We now demonstrate roles for the androgen receptor (...

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Main Authors: Cottle, Denny L., Kretzschmar, Kai, Schweiger, Pawel J., Quist, Sven R., Gollnick, Harald P., Natsuga, Ken, Aoyagi, Satoru, Watt, Fiona M.
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778892/
https://ncbi.nlm.nih.gov/pubmed/23403291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.01.013
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