Lung Clearance Index as an Outcome Measure for Clinical Trials in Young Children with Cystic Fibrosis. A Pilot Study Using Inhaled Hypertonic Saline

Rationale: Lung clearance index (LCI), measured by multiple breath washout (MBW), is a noninvasive measure of ventilation inhomogeneity that holds promise as an objective physiologic endpoint for clinical trials in infants and preschool children with cystic fibrosis (CF). Objectives: To study the fe...

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Main Authors: Subbarao, Padmaja, Stanojevic, Sanja, Brown, Meghan, Jensen, Renee, Rosenfeld, Margaret, Davis, Stephanie, Brumback, Lyndia, Gustafsson, Per, Ratjen, Felix
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778738/
https://ncbi.nlm.nih.gov/pubmed/23742699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201302-0219OC
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