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INHALED HYPERTONIC SALINE IN INFANTS AND CHILDREN LESS THAN SIX YEARS OF AGE WITH CYSTIC FIBROSIS: THE ISIS RANDOMIZED TRIAL

CONTEXT: Inhaled hypertonic saline is recommended as therapy for cystic fibrosis (CF) patients 6 years of age and older, but its efficacy has never been evaluated in CF patients <6 years of age. OBJECTIVE: To determine if hypertonic saline reduces the rate of protocol-defined pulmonary exacerbati...

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Autori principali: Rosenfeld, Margaret, Ratjen, Felix, Brumback, Lyndia, Daniel, Stephen, Rowbotham, Ron, McNamara, Sharon, Johnson, Robin, Kronmal, Richard, Davis, Stephanie D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586815/
https://ncbi.nlm.nih.gov/pubmed/22610452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2012.5214
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