Induction and Regulation of T-Cell Immunity by the Novel Tuberculosis Vaccine M72/AS01 in South African Adults

Rationale: Tuberculosis (TB) is a major cause of morbidity and mortality worldwide, thus there is an urgent need for novel TB vaccines. Objectives: We investigated a novel TB vaccine candidate, M72/AS01, in a phase IIa trial of bacille Calmette-Guérin–vaccinated, HIV-uninfected, and Mycobacterium tu...

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Hlavní autoři: Day, Cheryl L., Tameris, Michele, Mansoor, Nazma, van Rooyen, Michele, de Kock, Marwou, Geldenhuys, Hennie, Erasmus, Mzwandile, Makhethe, Lebohang, Hughes, E. Jane, Gelderbloem, Sebastian, Bollaerts, Anne, Bourguignon, Patricia, Cohen, Joe, Demoitié, Marie-Ange, Mettens, Pascal, Moris, Philippe, Sadoff, Jerald C., Hawkridge, Anthony, Hussey, Gregory D., Mahomed, Hassan, Ofori-Anyinam, Opokua, Hanekom, Willem A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778736/
https://ncbi.nlm.nih.gov/pubmed/23306546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201208-1385OC
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