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Human cap methyltransferase (RNMT) N-terminal non-catalytic domain mediates recruitment to transcription initiation sites

Gene expression in eukaryotes is dependent on the mRNA methyl cap which mediates mRNA processing and translation initiation. Synthesis of the methyl cap initiates with the addition of 7-methylguanosine to the initiating nucleotide of RNA pol II (polymerase II) transcripts, which occurs predominantly...

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Detalhes bibliográficos
Main Authors: Aregger, Michael, Cowling, Victoria H.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778707/
https://ncbi.nlm.nih.gov/pubmed/23863084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20130378
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