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Identification of promethazine as an amyloid-binding molecule using a fluorescence high-throughput assay and MALDI imaging mass spectrometry()

The identification of amyloid-binding compounds is a crucial step in the development of imaging probes and therapeutics for the detection and cure of Alzheimer's disease. Unfortunately, the process typically lags during the translation from in vitro to in vivo studies due to the impenetrable na...

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Autors principals: McClure, Richard A., Chumbley, Chad W., Reyzer, Michelle L., Wilson, Kevin, Caprioli, Richard M., Gore, John C., Pham, Wellington
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778261/
https://ncbi.nlm.nih.gov/pubmed/24179813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2013.04.015
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