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Characterization of Dynamics in Complex Lyophilized Formulations: I. Comparison of Relaxation Times Measured by Isothermal Calorimetry with Data Estimated from the Width of the Glass Transition Temperature Region

The purposes of this study are to characterize the relaxation dynamics in complex freeze dried formulations and to investigate the quantitative relationship between the structural relaxation time as measured by thermal activity monitor (TAM) and that estimated from the width of the glass transition...

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Autors principals: Chieng, Norman, Mizuno, Masayasu, Pikal, Michael
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778132/
https://ncbi.nlm.nih.gov/pubmed/23608636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2013.04.003
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