Phase II study of lutetium-177 labeled anti-prostate-specific membrane antigen (PSMA) monoclonal antibody J591 for metastatic castration-resistant prostate cancer

PURPOSE: To assess the efficacy of a single infusion of radiolabeled anti-prostate specific membrane antigen monoclonal antibody J591 ((177)Lu-J591) by PSA decline, measurable disease response, and survival. EXPERIMENTAL DESIGN: In this dual-center phase II study, 2 cohorts with progressive metastat...

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Autores principales: Tagawa, Scott T., Milowsky, Matthew I., Morris, Michael, Vallabhajosula, Shankar, Christos, Paul, Akhtar, Naveed H., Osborne, Joseph, Goldsmith, Stanley J., Larson, Steve, Taskar, Neeta Pandit, Scher, Howard I., Bander, Neil H., Nanus, David M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778101/
https://ncbi.nlm.nih.gov/pubmed/23714732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0231
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