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Phase II study of lutetium-177 labeled anti-prostate-specific membrane antigen (PSMA) monoclonal antibody J591 for metastatic castration-resistant prostate cancer

PURPOSE: To assess the efficacy of a single infusion of radiolabeled anti-prostate specific membrane antigen monoclonal antibody J591 ((177)Lu-J591) by PSA decline, measurable disease response, and survival. EXPERIMENTAL DESIGN: In this dual-center phase II study, 2 cohorts with progressive metastat...

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Detalhes bibliográficos
Main Authors: Tagawa, Scott T., Milowsky, Matthew I., Morris, Michael, Vallabhajosula, Shankar, Christos, Paul, Akhtar, Naveed H., Osborne, Joseph, Goldsmith, Stanley J., Larson, Steve, Taskar, Neeta Pandit, Scher, Howard I., Bander, Neil H., Nanus, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778101/
https://ncbi.nlm.nih.gov/pubmed/23714732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0231
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