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Disruption of the Endothelial Barrier by Proteases from the Bacterial Pathogen Pseudomonas aeruginosa: Implication of Matrilysis and Receptor Cleavage

Within the vasculature, uncontrolled pericellular proteolysis can lead to disruption of cell-to-cell and cell-to-matrix interactions and subsequent detachment-induced cell apoptosis, or anoikis, contributing to inflammatory vascular diseases, with the endothelium as the major target. Most studies so...

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Autors principals: Beaufort, Nathalie, Corvazier, Elisabeth, Mlanaoindrou, Saouda, de Bentzmann, Sophie, Pidard, Dominique
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777978/
https://ncbi.nlm.nih.gov/pubmed/24069438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075708
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