The Pseudomonas aeruginosa LasB Metalloproteinase Regulates the Human Urokinase-Type Plasminogen Activator Receptor through Domain-Specific Endoproteolysis

Pseudomonas aeruginosa is an opportunistic pathogen in human lungs, where its secretable LasB metalloproteinase can be a virulence factor. The urokinase-type plasminogen activator receptor (uPAR) participates in pericellular proteolysis and the adherence/migration of epithelial cells and leukocytes...

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Detalhes bibliográficos
Main Authors: Leduc, Dominique, Beaufort, Nathalie, de Bentzmann, Sophie, Rousselle, Jean-Claude, Namane, Abdelkader, Chignard, Michel, Pidard, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951998/
https://ncbi.nlm.nih.gov/pubmed/17517866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00015-07
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