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Independent Effects of Genetic Variations in Mannose-Binding Lectin Influence the Course of HIV Disease: The Advantage of Heterozygosity for Coding Mutations
BACKGROUND: The in vivo impact of mannose-binding lectin (MBL), a molecule involved in innate immunity, on the pathogenesis of human immunodeficiency virus (HIV)–1 infection and AIDS is unknown. METHODS: A total of 1102 HIV-positive and 2213 HIV-negative adult subjects were screened for polymorphism...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3777826/ https://ncbi.nlm.nih.gov/pubmed/18498240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/588712 |
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