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Role of CCL3L1-CCR5 Genotypes in the Epidemic Spread of HIV-1 and Evaluation of Vaccine Efficacy
BACKGROUND: Polymorphisms in CCR5, the major coreceptor for HIV, and CCL3L1, a potent CCR5 ligand and HIV-suppressive chemokine, are determinants of HIV-AIDS susceptibility. Here, we mathematically modeled the potential impact of these genetic factors on the epidemic spread of HIV, as well as on its...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2008
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2576446/ https://ncbi.nlm.nih.gov/pubmed/18989363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003671 |
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