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Small-molecule inhibition of inflammatory β-cell death

With the worldwide increase in diabetes prevalence there is a pressing unmet need for novel antidiabetic therapies. Insufficient insulin production due to impaired β-cell function and apoptotic reduction of β-cell mass is a common denominator in the pathogenesis of diabetes. Current treatments are d...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Lundh, Morten, Scully, Stephen S., Mandrup-Poulsen, Thomas, Wagner, Bridget K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777666/
https://ncbi.nlm.nih.gov/pubmed/24003935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.12158
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