Functional compensation of glutathione S-transferase M1 (GSTM1) null by another GST superfamily member, GSTM2

The gene for glutathione-S-transferase (GST) M1 (GSTM1), a member of the GST-superfamily, is widely studied in cancer risk with regard to the homozygous deletion of the gene (GSTM1 null), leading to a lack of corresponding enzymatic activity. Many of these studies have reported inconsistent findings...

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Hauptverfasser: Bhattacharjee, Pritha, Paul, Somnath, Banerjee, Mayukh, Patra, Deblina, Banerjee, Priyam, Ghoshal, Nanda, Bandyopadhyay, Arun, Giri, Ashok K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776957/
https://ncbi.nlm.nih.gov/pubmed/24048194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02704
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