Leucine-Rich α2-Glycoprotein Is a Novel Biomarker of Neurodegenerative Disease in Human Cerebrospinal Fluid and Causes Neurodegeneration in Mouse Cerebral Cortex

Leucine-rich α2-glycoprotein (LRG) is a protein induced by inflammation. It contains a leucine-rich repeat (LRR) structure and easily binds with other molecules. However, the function of LRG in the brain during aging and neurodegenerative diseases has not been investigated. Here, we measured human L...

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Detalhes bibliográficos
Main Authors: Miyajima, Masakazu, Nakajima, Madoka, Motoi, Yumiko, Moriya, Masao, Sugano, Hidenori, Ogino, Ikuko, Nakamura, Eri, Tada, Norihiro, Kunichika, Miyuki, Arai, Hajime
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776841/
https://ncbi.nlm.nih.gov/pubmed/24058569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074453
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