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Biodistribution and Subcellular Localization of an Unnatural Boron-Containing Amino Acid (Cis-ABCPC) by Imaging Secondary Ion Mass Spectrometry for Neutron Capture Therapy of Melanomas and Gliomas

The development of new boron-delivery agents is a high priority for improving the effectiveness of boron neutron capture therapy. In the present study, 1-amino-3-borono-cyclopentanecarboxylic acid (cis-ABCPC) as a mixture of its L- and D- enantiomers was evaluated in vivo using the B16 melanoma mode...

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書誌詳細
主要な著者: Chandra, Subhash, Barth, Rolf F., Haider, Syed A., Yang, Weilian, Huo, Tianyao, Shaikh, Aarif L., Kabalka, George W.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776788/
https://ncbi.nlm.nih.gov/pubmed/24058680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075377
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