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A Sensitive Capillary GC-MS Method for Analysis of Topiramate from Plasma Obtained from Single Dose Studies

Topiramate (Topamax®) is an antiepileptic medication used as adjunctive and monotherapy in patients with epilepsy and for migraine prophylaxis. A GC-MS assay was developed that was capable of detecting topiramate plasma concentrations following a single rectal or oral dose administration. Topiramate...

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Detalhes bibliográficos
Main Authors: Conway, Jeannine M., Birnbaum, Angela K., Marino, Susan E., Cloyd, James C., Remmel, Rory P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776594/
https://ncbi.nlm.nih.gov/pubmed/22223467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bmc.1749
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