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Folding and Binding of an Intrinsically Disordered Protein: Fast, but Not ‘Diffusion-Limited’

[Image: see text] Coupled folding and binding of intrinsically disordered proteins (IDPs) is prevalent in biology. As the first step toward understanding the mechanism of binding, it is important to know if a reaction is ‘diffusion-limited’ as, if this speed limit is reached, the association must pr...

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Библиографические подробности
Главные авторы: Rogers, Joseph M., Steward, Annette, Clarke, Jane
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2013
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776562/
https://ncbi.nlm.nih.gov/pubmed/23301700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja309527h
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