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SnoN facilitates ALK1–Smad1/5 signaling during embryonic angiogenesis
In endothelial cells, two type I receptors of the transforming growth factor β (TGF-β) family, ALK1 and ALK5, coordinate to regulate embryonic angiogenesis in response to BMP9/10 and TGF-β. Whereas TGF-β binds to and activates ALK5, leading to Smad2/3 phosphorylation and inhibition of endothelial ce...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3776356/ https://ncbi.nlm.nih.gov/pubmed/24019535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201208113 |
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