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SnoN functions as a tumour suppressor by inducing premature senescence
SnoN represses TGF-β signalling to promote cell proliferation and has been defined as a proto-oncogene partly due to its elevated expression in many human cancer cells. Although the anti-tumourigenic activity of SnoN has been suggested, the molecular basis for this has not been defined. We showed he...
Tallennettuna:
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2782089/ https://ncbi.nlm.nih.gov/pubmed/19745809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.250 |
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