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SnoN functions as a tumour suppressor by inducing premature senescence
SnoN represses TGF-β signalling to promote cell proliferation and has been defined as a proto-oncogene partly due to its elevated expression in many human cancer cells. Although the anti-tumourigenic activity of SnoN has been suggested, the molecular basis for this has not been defined. We showed he...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2782089/ https://ncbi.nlm.nih.gov/pubmed/19745809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.250 |
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