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pH sensing by FAK-His58 regulates focal adhesion remodeling
Intracellular pH (pHi) dynamics regulates diverse cellular processes, including remodeling of focal adhesions. We now report that focal adhesion kinase (FAK), a key regulator of focal adhesion remodeling, is a pH sensor responding to physiological changes in pH. The initial step in FAK activation is...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3776353/ https://ncbi.nlm.nih.gov/pubmed/24043700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201302131 |
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