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Development of a fluorescent monoclonal antibody-based assay to measure the allosteric effects of synthetic peptides on self-oligomerization of AGR2 protein

Many regulatory proteins are homo-oligomeric and designing assays that measure self-assembly will provide novel approaches to study protein allostery and screen for novel small molecule modulators of protein interactions. We present an assay to begin to define the biochemical determinants that regul...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gray, Terry A, Murray, Euan, Nowicki, Matthew W, Remnant, Lucy, Scherl, Alexander, Muller, Petr, Vojtesek, Borek, Hupp, Ted R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Publishing Ltd 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776338/
https://ncbi.nlm.nih.gov/pubmed/23780840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2299
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