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The Functional Significance of Synaptotagmin Diversity in Neuroendocrine Secretion

Synaptotagmins (syts) are abundant, evolutionarily conserved integral membrane proteins that play essential roles in regulated exocytosis in nervous and endocrine systems. There are at least 17 syt isoforms in mammals, all with tandem C-terminal C2 domains with highly variable capacities for Ca(2+)...

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Detalhes bibliográficos
Main Authors: Moghadam, Paanteha K., Jackson, Meyer B.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776153/
https://ncbi.nlm.nih.gov/pubmed/24065953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2013.00124
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