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Paradoxical proepileptic response to NMDA receptor blockade linked to cortical interneuron defect in stargazer mice
Paradoxical seizure exacerbation by anti-epileptic medication is a well-known clinical phenomenon in epilepsy, but the cellular mechanisms remain unclear. One possibility is enhanced network disinhibition by unintended suppression of inhibitory interneurons. We investigated this hypothesis in the st...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3776135/ https://ncbi.nlm.nih.gov/pubmed/24065886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00156 |
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