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Impaired secretion of interferons by dendritic cells from aged subjects to influenza: Role of histone modifications

Increased susceptibility to respiratory infections such as influenza is the hallmark of advancing age. The mechanisms underlying the impaired immune response to influenza are not well understood. In the present study, we have investigated the effect of advancing age on dendritic cell (DC) function b...

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Autori principali: Prakash, Sangeetha, Agrawal, Sudhanshu, Cao, Jia-ning, Gupta, Sudhir, Agrawal, Anshu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776111/
https://ncbi.nlm.nih.gov/pubmed/23007963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-012-9477-8
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