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Increased Reactivity of Dendritic Cells from Aged Subjects to Self-Antigen, the Human DNA

Diminished immune functions and chronic inflammation are hallmarks of aging. The underlying causes are not well understood. In this investigation, we show an increased reactivity of dendritic cells from aged subjects to self-antigens as one of the potential mechanism contributing to age-associated i...

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Detalhes bibliográficos
Main Authors: Agrawal, Anshu, Tay, Jia, Ton, Steven, Agrawal, Sudhanshu, Gupta, Sudhir
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2621318/
https://ncbi.nlm.nih.gov/pubmed/19124757
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