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Growth hormone and insulin-like growth factor-I alter hippocampal excitatory synaptic transmission in young and old rats
In rats, as in humans, normal aging is characterized by a decline in hippocampal-dependent learning and memory, as well as in glutamatergic function. Both growth hormone (GH) and insulin-like growth factor-I (IGF-I) levels have been reported to decrease with age, and treatment with either GH or IGF-...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer Netherlands
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3776110/ https://ncbi.nlm.nih.gov/pubmed/22851280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-012-9460-4 |
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