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Growth hormone and insulin-like growth factor-I alter hippocampal excitatory synaptic transmission in young and old rats

In rats, as in humans, normal aging is characterized by a decline in hippocampal-dependent learning and memory, as well as in glutamatergic function. Both growth hormone (GH) and insulin-like growth factor-I (IGF-I) levels have been reported to decrease with age, and treatment with either GH or IGF-...

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Hlavní autoři: Molina, Doris P., Ariwodola, Olusegun J., Weiner, Jeff L., Brunso-Bechtold, Judy K., Adams, Michelle M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776110/
https://ncbi.nlm.nih.gov/pubmed/22851280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-012-9460-4
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