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Genetic Testing Strategies in Newly Diagnosed Endometrial Cancer Patients Aimed at Reducing Morbidity or Mortality from Lynch Syndrome in the Index Case or Her Relatives
Endometrial cancer is the first malignancy in 50% of women with Lynch syndrome, an autosomal dominant cancer-prone syndrome caused by germline mutations in genes encoding components of the DNA mismatch repair (MMR) pathway. These women (2-4% of all those with endometrial cancer) are at risk of metac...
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| Natura: | Artigo |
| Lingua: | Inglês |
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Public Library of Science
2013
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3775889/ https://ncbi.nlm.nih.gov/pubmed/24056992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.eogt.b59a6e84f27c536e50db4e46aa26309c |
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