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Genetic Testing for Lynch Syndrome in Individuals Newly Diagnosed with Colorectal Cancer to Reduce Morbidity and Mortality from Colorectal Cancer in Their Relatives

Individuals with Lynch syndrome, sometimes referred to as hereditary non-polyposis colorectal cancer (HNPCC), have an increased risk of developing colorectal cancer (CRC) as well as other cancers. The increased risk is due to inherited mutations in mismatch repair (MMR) genes, which reduce the abili...

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Bibliografische gegevens
Hoofdauteurs: Coates, Ralph, Williams, Marc, Melillo, Stephanie, Gudgeon, Jim
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130897/
https://ncbi.nlm.nih.gov/pubmed/21743847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.RRN1246
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