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Genetic Testing for Lynch Syndrome in Individuals Newly Diagnosed with Colorectal Cancer to Reduce Morbidity and Mortality from Colorectal Cancer in Their Relatives

Individuals with Lynch syndrome, sometimes referred to as hereditary non-polyposis colorectal cancer (HNPCC), have an increased risk of developing colorectal cancer (CRC) as well as other cancers. The increased risk is due to inherited mutations in mismatch repair (MMR) genes, which reduce the abili...

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Detalhes bibliográficos
Main Authors: Coates, Ralph, Williams, Marc, Melillo, Stephanie, Gudgeon, Jim
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130897/
https://ncbi.nlm.nih.gov/pubmed/21743847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.RRN1246
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