Rare Variants in Calcium Homeostasis Modulator 1 (CALHM1) Found in Early Onset Alzheimer’s Disease Patients Alter Calcium Homeostasis

Calcium signaling in the brain is fundamental to the learning and memory process and there is evidence to suggest that its dysfunction is involved in the pathological pathways underlying Alzheimer’s disease (AD). Recently, the calcium hypothesis of AD has received support with the identification of...

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Detalhes bibliográficos
Main Authors: Rubio-Moscardo, Fanny, Setó-Salvia, Núria, Pera, Marta, Bosch-Morató, Mònica, Plata, Cristina, Belbin, Olivia, Gené, Gemma, Dols-Icardo, Oriol, Ingelsson, Martin, Helisalmi, Seppo, Soininen, Hilkka, Hiltunen, Mikko, Giedraitis, Vilmantas, Lannfelt, Lars, Frank, Ana, Bullido, MªJesús, Combarros, Onofre, Sánchez-Juan, Pascual, Boada, Mercè, Tárraga, Lluís, Pastor, Pau, Pérez-Tur, Jordi, Baquero, Miquel, Molinuevo, José L., Sánchez-Valle, Raquel, Fuentes-Prior, Pablo, Fortea, Juan, Blesa, Rafael, Muñoz, Francisco J., Lleó, Alberto, Valverde, Miguel A., Clarimón, Jordi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775809/
https://ncbi.nlm.nih.gov/pubmed/24069280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074203
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