Lack of Endogenous IL-10 Enhances Production of Proinflammatory Cytokines and Leads to Brucella abortus Clearance in Mice

IL-10 is a cytokine that regulates the balance between pathogen clearance and immunopathology. Brucella abortus is an intracellular bacterium that causes chronic disease in humans and domestic animals. Here we evaluated the contribution of IL-10 in host immune response and pathology during B. abortu...

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Main Authors: Corsetti, Patrícia P., de Almeida, Leonardo A., Carvalho, Natália B., Azevedo, Vasco, Silva, Teane M. A., Teixeira, Henrique C., Faria, Ana C., Oliveira, Sergio C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775771/
https://ncbi.nlm.nih.gov/pubmed/24069337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074729
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